AAPF1: AAP Foundation Future Horizons in Periodontology

Program Track: Student and New Periodontist (SNP) Series

Presenters

Description

This session will consist of two speakers that will share and discuss emerging science regarding the future of personalized periodontal medicine and its potential applications to contemporary clinical periodontology practice. The speakers are faculty and practitioners who have benefited from American Academy of Periodontology Foundation initiatives. Each speaker will give a 20-minute presentation, followed by five-minutes for discussion.

Overall Goals of the session:

To highlight the work of AAP Foundation supported periodontists/residents and to stimulate a network of future leaders in academics and private practice.

Ahmed El-Awady

Topic: Pharmacogenomics to Precision Prescriptions in Periodontal Patients.

Adverse drug reaction (ADRs) account for estimated 1 in 3 of all hospital adverse events and affect about 2 million hospital stays each year. This results in prolong hospital stays by 1.7 to 4.6 days for these inpatients each year. ADRs also affect outpatient settings as it accounts for estimated 1 million emergency department visits and over 3.5 million physician office visits per year. This subsequently results in about 125,000 hospital admissions. Although the pharmacopeia in dental practice is relatively small, it involves important classes of medications such as local anesthetics, sedatives, and analgesics. These medications entail serious side effects ranges from gastrointestinal upset to respiratory and CNS depression. Still, undertreated and persistent postoperative pain may increase morbidity, complication, and costs while decreasing patients’ satisfaction and quality of life. Recently, pharmacogenomics testing has been approved by the FDA as a practical method in personalizing medications to each individual in a safe and effective manner. This course offers insight about pharmacogenomics testing to formulate individualized-prescription plan to reduce adverse drug reaction and improve pain management during and after periodontal surgeries.

Educational Objectives:

  • • Outline the science behind pharmacogenomics and the transition towards clinical applications.
  • • Understand the outcome of combining pharmacogenomics and medical history data to tailor a personalized iv sedation and pain control prescriptions for periodontal patients.
  • • Review the ability of personalized prescription to achieve more efficacious pain management during and after periodontal surgery.

Flora Momen-Heravi

This course offers an exploration of periodontal disease pathogenesis and its intersection with immunotherapy, focusing on the cellular changes involved in periodontal disease and their implications for cancer and autoimmune diseases. Attendees will gain insights into the latest single-cell technologies that are revolutionizing our understanding of these relationships. Additionally, the course will cover the emerging role of artificial intelligence (AI) in diagnosing periodontal disease and its application in translational research. Participants will engage with cutting-edge research and discuss potential future directions in the field.

Educational Objectives:

  • • Explore the key cellular and molecular mechanisms underlying periodontal pathogenesis.
  • • Examine the impact of these cellular changes on overall oral health and systemic conditions.
  • • Introduce the principles and applications of single-cell technologies in periodontal research.
  • • Discuss how these technologies provide new insights into the relationship between periodontal disease, cancer, and autoimmune diseases.
  • • Analyze the role of the immune system in periodontal disease progression.
  • • Explore current and potential immunotherapeutic strategies for managing periodontal disease.
  • • Examine the connections between periodontal disease and systemic diseases such as cancer and autoimmune disorders.
  • • Review recent research findings and their clinical implications.
  • • Understand how AI is being utilized to improve the diagnosis of periodontal disease.
  • • Explore the role of AI in advancing translational research and its potential future applications.


  • CE Hours: .75


    Disclosure(s):
    Roger Arce, DDS MS PhD: No financial relationships to disclose
    Beatriz Bezerra, DDS, PhD: No financial relationships to disclose
    Ahmed El-Awady, B.D.S, M.S., PhD: No financial relationships to disclose
    Fatemeh Momen-Heravi, DDS, PhD, MPH, MS: No financial relationships to disclose